BIOPTERIN METABOLISM AND NITRIC OXIDE RECOUPLING IN CANCER

Biopterin metabolism and nitric oxide recoupling in cancer

Tetrahydrobiopterin is a Western Hats cofactor necessary for the activity of several enzymes, the most studied of which is nitric oxide synthase.The role of this cofactor-enzyme relationship in vascular biology is well established.Recently, tetrahydrobiopterin metabolism has received increasing attention in the field of cancer immunology and immuno

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